Dr. Mitra Assadi is director of the Headache Medicine and Pediatric Neurology at the Capital Institute for Neurosciences. Board certified in neurology and clinical neurophysiology, Dr. Assadi was among one of the first neurologists in the United States to obtain a board certification in headache medicine in 2008. Dr. Assadi is actively involved in teaching and research. She is a Professor of Neurology at Robert Wood Johnson Medical School and the Director of the Neurology Clerkship at Capital Health system. Dr. AssadiÃ¢â‚¬â„¢s research has mostly focused on neuro-genetic disorders, in particular leukodystrophies. She has served as a clinical investigator at the Center for Cell and Gene Therapy at the Rowan University since 2004. She has special expertise in Canavan Disease and her published research on the use of lithium in Canavan patients has established the standard of care for these patients in the scientific community
Preprocessing of electrophysiological signals EEG, MEG and IEEG, Separation between spikes and oscillations in MEG and IEEG in epilepsy, Despikifing IEEG signal to predict the buildup seizure, source localization of epileptic spikes and gamma oscillations, Epileptic brain dynamic mapping, embedding filtering methods using intelligent architecture. In the other hand she is thankful to her background as electrical engineer. She is also interested in developing neurofeedback and monitoring systems. In fact, enlarging solution and wellness for disabled people is among her research priority areas as elaborating efficient distance education programs (materials and software).
Sergei Y Funikov has completed his PhD at Engelhardt Institute of Molecular Biology-Russian Academy of Sciences. His main research focuses on studying the regulation of small non-coding RNAs (in particular, microRNAs and Piwi-interacting RNAs) in stress response as well as investigation of the immune and neuroprotective properties of human recombinant heat shock protein 70 (Hsp70). His study concerns the molecular aspects underlying the progression of motor neurons failure on the model recapitulating the clinical symptoms of amyotrophic lateral sclerosis.
The goal of my laboratory is to understand the molecular determinants of cortical circuit development and wiring in physiology and pathology. In particular, a main focus of the laboratory is to try to understand how diverse developing neurons influence one another during neuronal migration, axon and dendrite polarization, and formation of neuronal networks. Indeed, we believe that the extracellular milieu of a specific developing brain cell is strongly influenced by the presence of other cells that are developing themselves (cellular environment). Notably, as development is by definition a dynamic process, the cellular environment will constantly change over time and it will be different in different brain areas. This may have tremendous conceptual consequences for the treatment of neurodevelopmental disorders, and we believe that the study of the different cellular environments during brain development may eventually lead to the identification of specific therapeutic windows to address aberrant neuronal development with much reduced side effects. To address these issues, we have developed two lines of research in the laboratory: a first line focuses on basic and translational animal research on brain development in health and animal models of neurodevelopmental disorders, and a second one focuses on promoting new technological approaches in developmental neuroscience.
BS, Mathematics, Dallas Baptist University Mathematics, Texas Tech University Graduate School MD, Texas Tech Medical School Internship, General Surgery, University of Iowa Carver College of Medicine Resident, Neurosurgery, University of Iowa Carver College of Medicine Fellow, CNS Dandy fellowship in skull base surgery, University of Arkansas Hospitals and Clinics Chief Resident, Neurosurgery, University of Iowa Carver College of Medicine Fellow, Cerebrovascular, Barrow Neurological Institute Fellow, Cerebrovascular, Helsinki Central University Hospital Fellow, Diagnostic Angiogram, University of Virginia Hospitals and Clinics Fellow, Endovascular, Thomas Jefferson Hospital